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KDM5 family as therapeutic targets in breast cancer: Pathogenesis and therapeutic opportunities and challenges

Abstract Breast cancer (BC) is the most frequent malignant cancer diagnosis and is a primary factor for cancer deaths in women. The clinical subtypes of BC include estrogen receptor (ER) positive, progesterone receptor (PR) positive, human epidermal growth factor receptor 2 (HER2) positive, and trip...

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Principais autores: Chang-Yun Li, Wanhe Wang, Chung-Hang Leung, Guan-Jun Yang, Jiong Chen
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2024-05-01
סדרה:Molecular Cancer
נושאים:
Breast cancer
KDM5
Histone demethylation
Therapeutic target
KDM5 inhibitors
גישה מקוונת:https://doi.org/10.1186/s12943-024-02011-0
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