KDM5 family as therapeutic targets in breast cancer: Pathogenesis and therapeutic opportunities and challenges

Abstract Breast cancer (BC) is the most frequent malignant cancer diagnosis and is a primary factor for cancer deaths in women. The clinical subtypes of BC include estrogen receptor (ER) positive, progesterone receptor (PR) positive, human epidermal growth factor receptor 2 (HER2) positive, and trip...

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Principais autores:	Chang-Yun Li, Wanhe Wang, Chung-Hang Leung, Guan-Jun Yang, Jiong Chen
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2024-05-01
Series:	Molecular Cancer
Assuntos:	Breast cancer KDM5 Histone demethylation Therapeutic target KDM5 inhibitors
Acceso en liña:	https://doi.org/10.1186/s12943-024-02011-0
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