Therapeutic Potentials of Inhibition of Jumonji C Domaincontaining Demethylases in Acute Myeloid Leukemia

Objective: Acute myeloid leukemia (AML) is a complex disease affected by both genetic and epigenetic factors. Histone methylation and demethylation are types of epigenetic modification in chromatin remodeling and gene expression. Abnormal expression of histone demethylases is indicated in many types...

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Autores principales:	Duygu Koca, Nurcan Haştar, Selin Engür, Yağmur Kiraz, Gizem Tuğçe Ulu, Demet Çekdemir, Yusuf Baran
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Turkish Society of Hematology 2020-02-01
Colección:	Turkish Journal of Hematology
Materias:	acute myeloid leukemia methylstat jumonji c domain histone methylation
Acceso en línea:	https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-10734
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