Distinct oncogenic phenotypes in hematopoietic specific deletions of Trp53
Abstract Loss of function in the tumor suppressor gene TP53 is the most common alteration seen in human cancer. In mice, P53 deletion in all cells leads predominantly to the development of T-cell lymphomas, followed by B-cell lymphomas, sarcomas and teratomas. In order to dissect the role of P53 in...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Portfolio
2023-05-01
|
| Schriftenreihe: | Scientific Reports |
| Online-Zugang: | https://doi.org/10.1038/s41598-023-33949-8 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|