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First validated liquid chromatography–tandem mass spectrometry method for simultaneous quantification of propranolol and 4-hydroxypropranolol in pig plasma and dried blood spots and its application to a pharmacokinetic study

Background and Aim: Propranolol is a widely used non-selective beta-adrenergic blocker in human medicine, with well-characterized pharmacokinetics (PK) in humans but virtually no data available for pigs, a species of growing biomedical relevance. Furthermore, no validated bioanalytical methods exist...

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Principais autores: Anisa Bardhi, Domenico Ventrella, Alberto Elmi, Ronette Gehring, Davide Martelli, Ilaria Troisio, Maria Laura Bacci, Andrea Barbarossa
פורמט: Artigo
שפה:Inglês
יצא לאור: Veterinary World 2026-01-01
סדרה:Veterinary World
נושאים:
גישה מקוונת:https://veterinaryworld.org/Vol.19/January-2026/2.pdf
תגים: הוספת תג
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