First validated liquid chromatography–tandem mass spectrometry method for simultaneous quantification of propranolol and 4-hydroxypropranolol in pig plasma and dried blood spots and its application to a pharmacokinetic study

Background and Aim: Propranolol is a widely used non-selective beta-adrenergic blocker in human medicine, with well-characterized pharmacokinetics (PK) in humans but virtually no data available for pigs, a species of growing biomedical relevance. Furthermore, no validated bioanalytical methods exist...

Descrición completa

Detalles Bibliográficos

Principais autores:	Anisa Bardhi, Domenico Ventrella, Alberto Elmi, Ronette Gehring, Davide Martelli, Ilaria Troisio, Maria Laura Bacci, Andrea Barbarossa
Formato:	Artigo
Idioma:	Inglês
Publicado:	Veterinary World 2026-01-01
Series:	Veterinary World
Assuntos:	4-hydroxypropranolol beta-blocker dried blood spots liquid chromatography–tandem mass spectrometry microsampling pharmacokinetics pigs propranolol
Acceso en liña:	https://veterinaryworld.org/Vol.19/January-2026/2.pdf
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!