Development, initial validation, and application of a visual read method for [18F]MK‐6240 tau PET

Abstract Background The positron emission tomography (PET) radiotracer [18F]MK‐6240 exhibits high specificity for neurofibrillary tangles (NFTs) of tau protein in Alzheimer's disease (AD), high sensitivity to medial temporal and neocortical NFTs, and low within‐brain background. Objectives were to d...

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Principais autores:	Joanna L. Shuping, Dawn C. Matthews, Katarzyna Adamczuk, David Scott, Christopher C. Rowe, William C. Kreisl, Sterling C. Johnson, Ana S. Lukic, Keith A. Johnson, Pedro Rosa‐Neto, Randolph D. Andrews, Koen Van Laere, Lindsay Cordes, Larry Ward, Claire L. Wilde, Jerome Barakos, Derk D. Purcell, Davangere P. Devanand, Yaakov Stern, Jose A. Luchsinger, Cyrille Sur, Julie C. Price, Adam M. Brickman, William E. Klunk, Adam L. Boxer, Sulantha S. Mathotaarachchi, Patrick J. Lao, Jeffrey L. Evelhoch
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Wiley 2023-01-01
סדרה:	Alzheimer’s & Dementia: Translational Research & Clinical Interventions
נושאים:	Alzheimer's disease florquinitau neurofibrillary tangles positron emission tomography tau tracer
גישה מקוונת:	https://doi.org/10.1002/trc2.12372
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