New link between the RNA polymerase II-CTD and replication stress
Conflicts between transcription and replication are a major source of replication stress. Our recent findings show that proper dephosphorylation of Serine 5 in the carboxy-terminal domain (CTD) of DNA-directed RNA polymerase II subunit RPB1 is needed to prevent such conflicts in human cells.
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis Group
2021-05-01
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| Colecção: | Molecular & Cellular Oncology |
| Assuntos: | |
| Acesso em linha: | http://dx.doi.org/10.1080/23723556.2021.1910008 |
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