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New link between the RNA polymerase II-CTD and replication stress

Conflicts between transcription and replication are a major source of replication stress. Our recent findings show that proper dephosphorylation of Serine 5 in the carboxy-terminal domain (CTD) of DNA-directed RNA polymerase II subunit RPB1 is needed to prevent such conflicts in human cells.

Furkejuvvon:
Bibliográfalaš dieđut
Váldodahkkit: Helga B. Landsverk, Lise E. Sandquist, Lilli T. E. Bay, Randi G. Syljuåsen
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Taylor & Francis Group 2021-05-01
Ráidu:Molecular & Cellular Oncology
Fáttát:
Liŋkkat:http://dx.doi.org/10.1080/23723556.2021.1910008
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