Kinetic analysis of ASIC1a delineates conformational signaling from proton-sensing domains to the channel gate
Acid-sensing ion channels (ASICs) are neuronal Na+ channels that are activated by a drop in pH. Their established physiological and pathological roles, involving fear behaviors, learning, pain sensation, and neurodegeneration after stroke, make them promising targets for future drugs. Currently, the...
में बचाया:
| मुख्य लेखकों: | , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
eLife Sciences Publications Ltd
2021-03-01
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| श्रृंखला: | eLife |
| विषय: | |
| ऑनलाइन पहुंच: | https://elifesciences.org/articles/66488 |
| टैग: |
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