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A modified RMCE-compatible Rosa26 locus for the expression of transgenes from exogenous promoters.

Generation of gain-of-function transgenic mice by targeting the Rosa26 locus has been established as an alternative to classical transgenic mice produced by pronuclear microinjection. However, targeting transgenes to the endogenous Rosa26 promoter results in moderate ubiquitous expression and is not...

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Xehetasun bibliografikoak
Egile Nagusiak: Jan S Tchorz, Thomas Suply, Iwona Ksiazek, Claudio Giachino, Dimitri Cloëtta, Claus-Peter Danzer, Thierry Doll, Andrea Isken, Marianne Lemaistre, Verdon Taylor, Bernhard Bettler, Bernd Kinzel, Matthias Mueller
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2012-01-01
Saila:PLoS ONE
Sarrera elektronikoa:http://europepmc.org/articles/PMC3258265?pdf=render
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