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Expression of transgenes targeted to the Gt(ROSA)26Sor locus is orientation dependent.

Targeting transgenes to a chosen location in the genome has a number of advantages. A single copy of the DNA construct can be inserted by targeting into regions of chromatin that allow the desired developmental and tissue-specific expression of the transgene.In order to develop a reliable system for...

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Detaylı Bibliyografya
Asıl Yazarlar: Douglas Strathdee, Helen Ibbotson, Seth G N Grant
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2006-12-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC1762389?pdf=render
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