Dual fluorescent reporter pig for Cre recombination: transgene placement at the ROSA26 locus.
We are extending the Cre/loxP site-specific recombination system to pigs, focussing on conditional and tissue-specific expression of oncogenic mutations to model human cancers. Identifying the location, pattern and extent of Cre recombination in vivo is an important aspect of this technology. Here w...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2014-01-01
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| Serie: | PLoS ONE |
| Accesso online: | http://europepmc.org/articles/PMC4099177?pdf=render |
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