Repurposing dipeptidyl peptidase-4 inhibitor for Parkinson's disease prevention: A drug-target Mendelian randomization study

Parkinson's disease (PD) remains without effective disease-modifying therapies, primarily due to limited understanding of its underlying mechanisms. Emerging evidence suggests that dipeptidyl peptidase-4 inhibitors (DPP-4Is), commonly used as anti-diabetics, may offer neuroprotective effects. We aim...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Joo-Yeon Lee, Don Gueu Park, Joohon Sung
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-01-01
coleção:	Neurotherapeutics
Assuntos:	Mendelian randomization Parkinson's disease Drug repurposing Dipeptidyl peptidase-4 inhibitor
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1878747925002934
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!