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Repurposing dipeptidyl peptidase-4 inhibitor for Parkinson's disease prevention: A drug-target Mendelian randomization study

Parkinson's disease (PD) remains without effective disease-modifying therapies, primarily due to limited understanding of its underlying mechanisms. Emerging evidence suggests that dipeptidyl peptidase-4 inhibitors (DPP-4Is), commonly used as anti-diabetics, may offer neuroprotective effects. We aim...

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Príomhchruthaitheoirí: Joo-Yeon Lee, Don Gueu Park, Joohon Sung
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Elsevier 2026-01-01
Sraith:Neurotherapeutics
Ábhair:
Rochtain ar líne:http://www.sciencedirect.com/science/article/pii/S1878747925002934
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