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Metabolism of 4′-Chlorodiazepam and Diclazepam in Rat Liver Microsomes

To investigate the metabolic profiles of 4′-chlorodiazepam and diclazepam in vivo, the liver microsomal metabolism model was established. Firstly, the target substances were incubated in the water bath pot at 37 ℃ for about 4 h. Then the incubation buffer was terminated by ice acetonitrile. After th...

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Bibliografische gegevens
Hoofdauteurs: LI Le1,2, ZHAO Jun-bo2, YAN Hui2, DENG Hong-xiao2, FAN Xian-yu2, LIU Wan-hui1, XIANG Ping2
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Editorial Board of Journal of Chinese Mass Spectrometry Society 2022-01-01
Reeks:Zhipu Xuebao
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Online toegang:http://www.jcmss.com.cn/CN/article/openArticlePDF.jsp?attachType=PDF&id=3044
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