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Characterization of CYPs and UGTs Involved in Human Liver Microsomal Metabolism of Osthenol

Osthenol is a prenylated coumarin isolated from the root of Angelica koreana and Angelica dahurica, and is an O-demethylated metabolite of osthole in vivo. Its various pharmacological effects have been reported previously. The metabolic pathway of osthenol was partially confirmed in rat osthole stud...

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Autores principales: Pil Joung Cho, Sanjita Paudel, Doohyun Lee, Yun Ji Jin, GeunHyung Jo, Tae Cheon Jeong, Sangkyu Lee, Taeho Lee
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2018-08-01
Colección:Pharmaceutics
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Acceso en línea:http://www.mdpi.com/1999-4923/10/3/141
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