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Assessing Drug Interaction and Pharmacokinetics of Loxoprofen in Mice Treated with CYP3A Modulators

Loxoprofen (LOX) is a non-selective cyclooxygenase inhibitor that is widely used for the treatment of pain and inflammation caused by chronic and transitory conditions. Its alcoholic metabolites are formed by carbonyl reductase (CR) and they consist of trans-LOX, which is active, and cis-LOX, which...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Sanjita Paudel, Aarajana Shrestha, Piljoung Cho, Riya Shrestha, Younah Kim, Taeho Lee, Ju-Hyun Kim, Tae Cheon Jeong, Eung-Seok Lee, Sangkyu Lee
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: MDPI AG 2019-09-01
Цуврал:Pharmaceutics
Нөхцлүүд:
Онлайн хандалт:https://www.mdpi.com/1999-4923/11/9/479
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