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Assessing Drug Interaction and Pharmacokinetics of Loxoprofen in Mice Treated with CYP3A Modulators

Loxoprofen (LOX) is a non-selective cyclooxygenase inhibitor that is widely used for the treatment of pain and inflammation caused by chronic and transitory conditions. Its alcoholic metabolites are formed by carbonyl reductase (CR) and they consist of trans-LOX, which is active, and cis-LOX, which...

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Autors principals: Sanjita Paudel, Aarajana Shrestha, Piljoung Cho, Riya Shrestha, Younah Kim, Taeho Lee, Ju-Hyun Kim, Tae Cheon Jeong, Eung-Seok Lee, Sangkyu Lee
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2019-09-01
Col·lecció:Pharmaceutics
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Accés en línia:https://www.mdpi.com/1999-4923/11/9/479
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