Zfp57 Exerts Maternal and Sexually Dimorphic Effects on Genomic Imprinting

Zfp57 has both maternal and zygotic functions in mouse. It maintains genomic imprinting at most known imprinted regions and controls allelic expression of the target imprinted genes in mouse embryos. The DNA methylation imprint at many imprinting control regions (ICRs) is lost when both maternal and...

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Detalhes bibliográficos

Principais autores:	Zhen Xu, Jiajia Shi, Yu Zhang, Yuhan Liu, Junzheng Zhao, Qian Chen, Chenglin Song, Shuhui Geng, Wei Xie, Feizhen Wu, Yun Bai, Yang Yang, Xiajun Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-02-01
coleção:	Frontiers in Cell and Developmental Biology
Assuntos:	genomic imprinting imprinting control region (ICR) imprinted genes maternal effect gender, sexually dimorphic allelic expression, RNA-seq
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcell.2022.784128/full
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