ZFP57 regulates DNA methylation of imprinted genes to facilitate embryonic development of somatic cell nuclear transfer embryos in Holstein cows

ABSTRACT: Aberrant epigenetic nuclear reprogramming, especially imprinting pattern disorders, is one of the major causes of failure of clone development from somatic cell nuclear transfer (SCNT). Previous studies showed that ZFP57 is a key protein required for imprint maintenance after fertilization...

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Detalhes bibliográficos

Principais autores:	Tong Yu, Ru Meng, Weijia Song, Hongzheng Sun, Quanli An, Chengtu Zhang, Yong Zhang, Jianmin Su
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-01-01
Colecção:	Journal of Dairy Science
Assuntos:	nuclear reprogramming barrier ZFP57 imprinted genes DNA methylation embryonic development
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022030222006683
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