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ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains

Abstract Background KRAB zinc finger proteins (KZFPs) represent one of the largest families of DNA-binding proteins in vertebrate genomes and appear to have evolved to silence transposable elements (TEs) including endogenous retroviruses through sequence-specific targeting of repressive chromatin st...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Hui Shi, Ruslan Strogantsev, Nozomi Takahashi, Anastasiya Kazachenka, Matthew C. Lorincz, Myriam Hemberger, Anne C. Ferguson-Smith
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2019-08-01
Schriftenreihe:Epigenetics & Chromatin
Schlagworte:
DNA methylation
KZFPs
ZFP57
Transposable elements
Embryonic stem cells
Online-Zugang:http://link.springer.com/article/10.1186/s13072-019-0295-4
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