Synthetic DNA fragments bearing ICR cis elements become differentially methylated and recapitulate genomic imprinting in transgenic mice
Abstract Background Genomic imprinting is governed by allele-specific DNA methylation at imprinting control regions (ICRs), and the mechanism controlling its differential methylation establishment during gametogenesis has been a subject of intensive research interest. However, recent studies have re...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BMC
2018-06-01
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| Reeks: | Epigenetics & Chromatin |
| Onderwerpen: | |
| Online toegang: | http://link.springer.com/article/10.1186/s13072-018-0207-z |
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