Antibody accessibility determines location of spike surface mutations in SARS-CoV-2 variants.
The steady emergence of SARS-CoV-2 variants gives us a real-time view of the interplay between viral evolution and the host immune defense. The spike protein of SARS-CoV-2 is the primary target of antibodies. Here, we show that steric accessibility to antibodies provides a strong predictor of mutati...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2023-01-01
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| coleção: | PLoS Computational Biology |
| Acesso em linha: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1010822&type=printable |
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