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Antibody accessibility determines location of spike surface mutations in SARS-CoV-2 variants.

The steady emergence of SARS-CoV-2 variants gives us a real-time view of the interplay between viral evolution and the host immune defense. The spike protein of SARS-CoV-2 is the primary target of antibodies. Here, we show that steric accessibility to antibodies provides a strong predictor of mutati...

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Detaylı Bibliyografya
Asıl Yazarlar: Sören von Bülow, Mateusz Sikora, Florian E C Blanc, Roberto Covino, Gerhard Hummer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2023-01-01
Seri Bilgileri:PLoS Computational Biology
Online Erişim:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1010822&type=printable
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