Aptamer-based approaches for sensitive detection and epitope mapping of SARS-CoV-2 spike protein

The SARS-CoV-2 spike (S) protein, crucial for viral entry, remains a key target for diagnostics and therapeutics amid evolving variants. Here, we describe the selection and characterization of novel DNA aptamers targeting the S1 subunit, including the Omicron strain, via systematic evolution of liga...

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المؤلفون الرئيسيون:	Suttinee Poolsup, Elnaz Yaghoobi, Aliaksandra Radchanka, Nandanee Mulloo, Spencer Uguccioni, John Paul Pezacki, Abdullah Khraibah, Aasha Jawad, Gurcharan K. Uppal, Yuxuan Gu, Benjamin Patrick Lapointe, Nico Hüttmann, Zoran Minic, Polina V. Artyushenko, Irina A. Shchugoreva, Anastasia V. Rogova, Felix N. Tomilin, Dmitry Morozov, Anna S. Kichkailo, Olga S. Kolovskaya, Maxim V. Berezovski
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Elsevier 2026-03-01
سلاسل:	Molecular Therapy: Nucleic Acids
الموضوعات:	MT: oligonucleotides: diagnostics and biosensors DNA aptamers to SARS-CoV-2 S1 subunit COVID-19 diagnostics protein binding epitopes proximity ligation of aptamers biolayer interferometry assay
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2162253125003440
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!