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Transcriptional and Non-Transcriptional Activation, Posttranslational Modifications, and Antiviral Functions of Interferon Regulatory Factor 3 and Viral Antagonism by the SARS-Coronavirus

The immune system defends against invading pathogens through the rapid activation of innate immune signaling pathways. Interferon regulatory factor 3 (IRF3) is a key transcription factor activated in response to virus infection and is largely responsible for establishing an antiviral state in the in...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Anna Glanz, Sukanya Chakravarty, Merina Varghese, Anita Kottapalli, Shumin Fan, Ritu Chakravarti, Saurabh Chattopadhyay
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-03-01
Schriftenreihe:Viruses
Schlagworte:
IRF3
interferon
posttranslational modifications
RIPA
innate antiviral immunity
viral antagonism
Online-Zugang:https://www.mdpi.com/1999-4915/13/4/575
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