A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study
A new lead compound has been designed as an antiangiogenic EGFR inhibitor that has the pharmacophoric characteristics to bind with the catalytic pocket of EGFR protein. The designed lead compound is a (para-chloro)acetamide derivative of the alkaloid, theobromine, (<b>T-1-PCPA</b>). At first, we sta...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2023-01-01
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| Colecção: | Life |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/2075-1729/13/1/191 |
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