Computer-assisted drug discovery (CADD) of an anti-cancer derivative of the theobromine alkaloid inhibiting VEGFR-2
VEGFR-2 is a significant target in cancer treatment, inhibiting angiogenesis and impeding tumor growth. Utilizing the essential pharmacophoric structural properties, a new semi-synthetic theobromine analogue (T-1-MBHEPA) was designed as VEGFR-2 inhibitor. Firstly, T-1-MBHEPA's stability and reactivi...
Збережено в:
| Автори: | , , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Springer
2023-12-01
|
| Серія: | Saudi Pharmaceutical Journal |
| Предмети: | |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S131901642300347X |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|