CRISPR‐Cas9–Mediated Genome Editing Confirms EPDR1 as an Effector Gene at the BMD GWAS‐Implicated ‘STARD3NL’ Locus

ABSTRACT Genome‐wide–association studies (GWASs) have discovered genetic signals robustly associated with BMD, but typically not the precise localization of effector genes. By intersecting genome‐wide promoter‐focused Capture C and assay for transposase‐accessible chromatin using sequencing (ATAC‐se...

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Bibliografski detalji

Glavni autori:	James A Pippin, Alessandra Chesi, Yadav Wagley, Chun Su, Matthew C Pahl, Kenyaita M Hodge, Matthew E Johnson, Andrew D Wells, Kurt D Hankenson, Struan F A Grant
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 2021-09-01
Serija:	JBMR Plus
Teme:	BONE MINERAL DENSITY (BMD) CHROMATIN CAPTURE CRISPR OSTEOBLAST DIFFERENTIATION OSTEOBLAST PROGENITOR
Online pristup:	https://doi.org/10.1002/jbm4.10531
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