Dietary disodium fumarate supplementation alleviates subacute ruminal acidosis (SARA)-induced liver damage by inhibiting pyroptosis via mitophagy-NLRP3 inflammasome pathway in lactating Hu sheep

Liver damage is common in ruminants with subacute ruminal acidosis (SARA). Disodium fumarate (DF) could regulate rumen microbial community and neutralize ruminal organic acids. This study aimed to evaluate the effect of dietary DF supplementation on SARA-induced liver damage and investigate the unde...

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Автори:	Hongzhu Zhang, Huimin Shi, Shendong Zhou, Guozhen Wei, Wan Xie, Meijuan Meng, Guangjun Chang, Xiangzhen Shen
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2023-05-01
Серія:	Frontiers in Immunology
Предмети:	SARA liver damage NLRP3 inflammasome pyroptosis mitophagy
Онлайн доступ:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1197133/full
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