Dietary disodium fumarate supplementation alleviates subacute ruminal acidosis (SARA)-induced liver damage by inhibiting pyroptosis via mitophagy-NLRP3 inflammasome pathway in lactating Hu sheep

Liver damage is common in ruminants with subacute ruminal acidosis (SARA). Disodium fumarate (DF) could regulate rumen microbial community and neutralize ruminal organic acids. This study aimed to evaluate the effect of dietary DF supplementation on SARA-induced liver damage and investigate the unde...

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Autors principals:	Hongzhu Zhang, Huimin Shi, Shendong Zhou, Guozhen Wei, Wan Xie, Meijuan Meng, Guangjun Chang, Xiangzhen Shen
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-05-01
Col·lecció:	Frontiers in Immunology
Matèries:	SARA liver damage NLRP3 inflammasome pyroptosis mitophagy
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1197133/full
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