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Acetylation regulates WRN catalytic activities and affects base excision DNA repair.

The Werner protein (WRN), defective in the premature aging disorder Werner syndrome, participates in a number of DNA metabolic processes, and we have been interested in the possible regulation of its function in DNA repair by post-translational modifications. Acetylation mediated by histone acetyltr...

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Bibliográfalaš dieđut
Váldodahkkit: Meltem Muftuoglu, Rika Kusumoto, Elzbieta Speina, Gad Beck, Wen-Hsing Cheng, Vilhelm A Bohr
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2008-04-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC2276247?pdf=render
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