Acetylation regulates WRN catalytic activities and affects base excision DNA repair.
The Werner protein (WRN), defective in the premature aging disorder Werner syndrome, participates in a number of DNA metabolic processes, and we have been interested in the possible regulation of its function in DNA repair by post-translational modifications. Acetylation mediated by histone acetyltr...
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| Principais autores: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2008-04-01
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| Serier: | PLoS ONE |
| Online adgang: | http://europepmc.org/articles/PMC2276247?pdf=render |
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