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Nardilysin in adipocyte regulates insulin sensitivity via HIF1α and PPARγ

Abstract Obesity is a critical global health issue and a major risk factor for type 2 diabetes mellitus (T2DM). However, molecular mechanism by which obesity leads to T2DM has not been fully elucidated. Here, we investigated the role of adipocyte nardilysin (NRDC) in insulin sensitivity using adipoc...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Principais autores: Shintaro Matsuda, Mikiko Ohno, Kiyoto Nishi, Shinya Ikeda, Hirotaka Iwasaki, Taiki Eifuku, Yoshinori Hiraoka, Takeshi Kimura, Koh Ono, Eiichiro Nishi
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2025-10-01
סדרה:Scientific Reports
נושאים:
גישה מקוונת:https://doi.org/10.1038/s41598-025-21276-z
תגים: הוספת תג
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