Roles of conserved active site residues in the IscS cysteine desulfurase reaction

Escherichia coli cysteine desulfurase (CD), IscS, modifies basal metabolism by transferring sulphur (S) from L-cysteine to numerous cellular pathways, whereas NFS1, a human CD, is active only in the formation of the [Acp]2:[ISD11]2:[NFS1]2 complex. Despite the accumulation of red-coloured IscS in E....

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Бібліографічні деталі
Автори:	Yilin Pang, Jing Wang, Xueping Gao, Mengyao Jiang, Lifei Zhu, Feng Liang, Mengxiang Liang, Xiaolin Wu, Xianxian Xu, Xiaojun Ren, Ting Xie, Wu Wang, Qianqian Sun, Xiaojun Xiong, Jianxin Lyu, Jianghui Li, Guoqiang Tan
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2023-02-01
Серія:	Frontiers in Microbiology
Предмети:	cysteine desulfurase pyridoxal 5′-phosphate active site residues Cys-aldimine Cys-ketimine antimicrobial resistance
Онлайн доступ:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1084205/full
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Roles of conserved active site residues in the IscS cysteine desulfurase reaction

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