Feature selection enhances peptide binding predictions for TCR-specific interactions

IntroductionT-cell receptors (TCRs) play a critical role in the immune response by recognizing specific ligand peptides presented by major histocompatibility complex (MHC) molecules. Accurate prediction of peptide binding to TCRs is essential for advancing immunotherapy, vaccine design, and understa...

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Podrobná bibliografie

Hlavní autoři:	Hamid Teimouri, Zahra S. Ghoreyshi, Anatoly B. Kolomeisky, Jason T. George
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-01-01
Edice:	Frontiers in Immunology
Témata:	immune response feature selection physicochemical properties TCR-peptide interactions binding affinity
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1510435/full
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