Evaluating Preclinical‐to‐Human Bioavailability Classification Using Smooth ROC Curve Estimation

ABSTRACT Human oral bioavailability is a critical pharmacokinetic parameter that determines systemic drug exposure, informs dose selection, and guides compound prioritization during early‐stage drug development. Although animal models are routinely employed to estimate human bioavailability, intersp...

Celý popis

Podrobná bibliografie

Hlavní autor:	Mahmut Sami Erdoğan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2026-05-01
Edice:	CPT: Pharmacometrics & Systems Pharmacology
Témata:	Bernstein polynomial nonparametric estimation oral bioavailability ROC curve smooth classification
On-line přístup:	https://doi.org/10.1002/psp4.70248
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!