Evaluating Preclinical‐to‐Human Bioavailability Classification Using Smooth ROC Curve Estimation
ABSTRACT Human oral bioavailability is a critical pharmacokinetic parameter that determines systemic drug exposure, informs dose selection, and guides compound prioritization during early‐stage drug development. Although animal models are routinely employed to estimate human bioavailability, intersp...
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Wiley
2026-05-01
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| Col·lecció: | CPT: Pharmacometrics & Systems Pharmacology |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1002/psp4.70248 |
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