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Evaluating Preclinical‐to‐Human Bioavailability Classification Using Smooth ROC Curve Estimation

ABSTRACT Human oral bioavailability is a critical pharmacokinetic parameter that determines systemic drug exposure, informs dose selection, and guides compound prioritization during early‐stage drug development. Although animal models are routinely employed to estimate human bioavailability, intersp...

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Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoir: Mahmut Sami Erdoğan
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Wiley 2026-05-01
Sraith:CPT: Pharmacometrics & Systems Pharmacology
Ábhair:
Rochtain ar líne:https://doi.org/10.1002/psp4.70248
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