NLRP3 activation induces BBB disruption and neutrophil infiltration via CXCR2 signaling in the mouse brain
Abstract NLRP3 is an intracellular sensor molecule that affects neutrophil functionality and infiltration in brain disorders such as experimental autoimmune encephalomyelitis (EAE). However, the detailed molecular mechanisms underlying the role of NLRP3 in these processes remain unknown. We found th...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2025-05-01
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| Serier: | Journal of Neuroinflammation |
| Fag: | |
| Online adgang: | https://doi.org/10.1186/s12974-025-03468-6 |
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