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Oxidative stress and endoplasmic reticulum stress in acute kidney injury: mechanistic crosstalk and therapeutic modulation

Acute kidney injury (AKI) is a complex syndrome with multiple causes, associated with high morbidity and mortality rates. Despite advances in intensive care, effective therapeutic strategies for AKI remain limited. In this review, we examine the roles of oxidative stress and endoplasmic reticulum st...

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Principais autores: Xiaoqi Xu, Qiongqiong Xing, Hanqing Li, Zichao Ding, Xianqing Ren
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-05-01
Serier:Frontiers in Medicine
Fag:
acute kidney injury
apoptosis
autophagy
endoplasmic reticulum stress
oxidative stress
Online adgang:https://www.frontiersin.org/articles/10.3389/fmed.2026.1808254/full
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