Oxidative stress and endoplasmic reticulum stress in acute kidney injury: mechanistic crosstalk and therapeutic modulation

Acute kidney injury (AKI) is a complex syndrome with multiple causes, associated with high morbidity and mortality rates. Despite advances in intensive care, effective therapeutic strategies for AKI remain limited. In this review, we examine the roles of oxidative stress and endoplasmic reticulum st...

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Autores principales:	Xiaoqi Xu, Qiongqiong Xing, Hanqing Li, Zichao Ding, Xianqing Ren
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2026-05-01
Colección:	Frontiers in Medicine
Materias:	acute kidney injury apoptosis autophagy endoplasmic reticulum stress oxidative stress
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1808254/full
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