Oxidative stress and endoplasmic reticulum stress in acute kidney injury: mechanistic crosstalk and therapeutic modulation

Acute kidney injury (AKI) is a complex syndrome with multiple causes, associated with high morbidity and mortality rates. Despite advances in intensive care, effective therapeutic strategies for AKI remain limited. In this review, we examine the roles of oxidative stress and endoplasmic reticulum st...

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Autors principals:	Xiaoqi Xu, Qiongqiong Xing, Hanqing Li, Zichao Ding, Xianqing Ren
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-05-01
Col·lecció:	Frontiers in Medicine
Matèries:	acute kidney injury apoptosis autophagy endoplasmic reticulum stress oxidative stress
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1808254/full
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