Single cell RNA-seq reveals cellular and transcriptional heterogeneity in the splenic CD11b+Ly6Chigh monocyte population expanded in sepsis-surviving mice

Abstract Background Sepsis survivors exhibit immune dysregulation that contributes to poor long-term outcomes. Phenotypic and functional alterations within the myeloid compartment are believed to be a contributing factor. Here we dissect the cellular and transcriptional heterogeneity of splenic CD11...

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主要な著者:	Haruki Watanabe, Minakshi Rana, Myoungsun Son, Pui Yan Chiu, Yurong Fei-Bloom, Kwangmin Choi, Betty Diamond, Barbara Sherry
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2024-11-01
シリーズ:	Molecular Medicine
主題:	Sepsis CLP CD11b+Ly6Chigh Phagocytosis Glycolysis scRNA-seq
オンライン･アクセス:	https://doi.org/10.1186/s10020-024-00970-0
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