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Homologous peptides derived from influenza A, B and C viruses induce variable CD8+ T cell responses with cross‐reactive potential

Abstract Objective Influenza A, B and C viruses (IAV, IBV and ICV, respectively) circulate globally, infecting humans and causing widespread morbidity and mortality. Here, we investigate the T cell response towards an immunodominant IAV epitope, NP265‐273, and its IBV and ICV homologues, presented b...

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Principais autores: Andrea T Nguyen, Hiu Ming Peter Lau, Hannah Sloane, Dhilshan Jayasinghe, Nicole A Mifsud, Demetra SM Chatzileontiadou, Emma J Grant, Christopher Szeto, Stephanie Gras
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2022-01-01
coleção:Clinical & Translational Immunology
Assuntos:
CD8+ T cell
cross‐reactivity
HLA
immune response
immunodominant epitope
Influenza
Acesso em linha:https://doi.org/10.1002/cti2.1422
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