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Public T cell clonotypes are selected in HLA-B∗57:01+/HIV+ patients independently of the viral load

Summary: HIV controllers can control viral replication and remain healthy, but the mechanism behind this control is unknown. Despite human leukocyte antigen (HLA) diversity in the population, almost 50% of HIV controllers express the HLA-B∗57:01 molecule, which presents, among others, the Gag-derive...

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Principais autores: Demetra S.M. Chatzileontiadou, Christian A. Lobos, Hayden Robson, Coral-Ann Almedia, Christopher Szeto, Alison Castley, Lloyd J. D’Orsogna, Stephanie Gras
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2024-08-01
Series:Cell Reports
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2211124724008842
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