Deep exploration of the TCR CDR3β repertoire specific for viral CD4 T-cell epitopes inside the circulating T-cell repertoire

IntroductionThis study provides an in-depth analysis of the diversity of the CD4 TCR CDR3β repertoire specific to influenza A (HA) and Epstein-Barr virus (EBNA) epitopes.MethodsEpitope-specific CD4 T cells from 13 healthy donors were enriched using a short-term culture step, isolated based on activa...

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Үндсэн зохиолчид:	Gautier Lhomme, Rémi Giraudet, Valéria Porcheddu, Evelyne Correia, Robert Olaso, Stephane Hua, Bernard Maillere
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2025-11-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	TCR clonotypes repertoire viral epitopes HLA class II
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1713225/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!