Acyl-CoA synthetase long-chain family member 4—A novel prognostic marker in cutaneous melanoma

Ferroptosis is an iron-dependent form of regulated cell death driven by lipid peroxidation. Acyl coenzyme A (Acyl-CoA) synthetase long-chain family member 4 (ACSL4) promotes ferroptosis by enriching cellular membranes with polyunsaturated fatty acids, yet its prognostic relevance in melanoma remains...

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Autors principals:	Soumya Paria, Rebecca Lapides, Babak Saravi, Anjali Rajagopal, Alina M. Torrez, Peter Kölblinger, Michael Wang-Evers, Dieter Manstein, Alexander A. Navarini, Peter Lazar, Lajos V. Kemény, Grzegorz Sarek, Kaustubh Adhikari, István B. Németh, Elisabeth Roider
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-03-01
Col·lecció:	Frontiers in Medicine
Matèries:	ACSL4 ferroptosis cutaneous melanoma survival analysis immune cell infiltration prognostic marker
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1553961/full
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