RIPK1 is dispensable for cell death regulation in β-cells during hyperglycemia

Objective: Receptor-interacting protein kinase 1 (RIPK1) orchestrates the decision between cell survival and cell death in response to tumor necrosis factor (TNF) and other cytokines. Whereas the scaffolding function of RIPK1 is crucial to prevent TNF-induced apoptosis and necroptosis, its kinase ac...

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Hlavní autoři:	Önay Veli, Öykü Kaya, Ana Beatriz Varanda, Ximena Hildebrandt, Peng Xiao, Yann Estornes, Matea Poggenberg, Yuan Wang, Manolis Pasparakis, Mathieu J.M. Bertrand, Henning Walczak, Alessandro Annibaldi, Alessandra K. Cardozo, Nieves Peltzer
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-09-01
Edice:	Molecular Metabolism
Témata:	RIPK1 Necroptosis TNF Apoptosis β-cell Diabetes
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2212877824001194
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